Eight U.S. Presidents have died in office. Of those eight, seven were elected in a year that ended in zero. The only exception was Zachary Taylor who was elected in 1848, but President Taylor died in 1850. Maybe President Ronald Reagan broke the Curse of Tippecanoe? Maybe President George W. Bush broke the curse? Maybe curses aren't real and this is all coincidental? But if Tenskwatawa "The Prophet" truly attempted to curse William Henry Harrison and have he and every Great Chief chosen every twenty years die, then it's safe to say he was successful.